产品详情
产品名称TRβ1 (phospho-Ser142) Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB,ELISA
种属反应性Human;Mouse;Rat
特异性Phospho-TRβ1 (S142) Polyclonal Antibody detects endogenous levels of TRβ1 protein only when phosphorylated at S142.
免疫原描述The antiserum was produced against synthesized peptide derived from human TR-beta1 around the phosphorylation site of Ser142. AA range:116-165
标记Unconjugated
别名THRB; ERBA2; NR1A2; THR1; Thyroid hormone receptor beta; Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta
数据库入口号Swiss Prot:P10828
GeneID:7068
Uniprot
P10828
实际分子量45
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
Western Blot: 1/500 - 1/2000.
ELISA: 1/5000. Not yet tested in other applications.
thyroid hormone receptor beta(THRB) Homo sapiens The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008],
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et al,Serine Supplementation Attenuates High-Selenium-Induced Insulin Resistance via Feedback Inhibition of PHGDH in Mice
, (2025),
PMID:
41264177
Yes
