产品详情
产品名称Numb (phospho-Ser276) rabbit pAb
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
应用WB
种属反应性Human
特异性This antibody detects endogenous levels of Human Numb (phospho-Ser276)
免疫原描述Synthesized phosho peptide around human Numb (Ser276)
标记Unconjugated
别名Protein numb homolog (h-Numb) (Protein S171)
数据库入口号Swiss Prot:P49757
GeneID:8650
Uniprot
P49757
实际分子量70
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
WB 1:1000-2000
NUMB, endocytic adaptor protein(NUMB) Homo sapiens The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
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et al,Prolonged Fructose Overconsumption Activates Original Biosynthetic and Metabolic Pathways of Endogenous Purine in Rats
, (2025),
PMID:
40442934
et al,Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota …
, (2025),
PMID:
41109441
Yes
