产品详情
产品名称Lck (phospho-Ser540) Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB,ELISA
种属反应性Human;Mouse;Rat
特异性Phospho-Lck (S540) Polyclonal Antibody detects endogenous levels of Lck protein only when phosphorylated at S540.
免疫原描述The antiserum was produced against synthesized peptide derived from human LCK around the phosphorylation site of Ser59. AA range:26-75
标记Unconjugated
别名LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK
数据库入口号Swiss Prot:P06239
GeneID:3932
Uniprot
P06239
实际分子量58
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
Western Blot: 1/500 - 1/2000.
ELISA: 1/40000. Not yet tested in other applications.
LCK proto-oncogene, Src family tyrosine kinase(LCK) Homo sapiens This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016],
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et al,A Radiofluorinated Nanobody PET Tracer to Dynamically Visualize Differential Nectin4 Expression In Vivo
, (2025),
PMID:
41037820
Yes
