产品详情
产品名称ERα (phospho-Ser104) Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB;IHC;IF;ELISA
种属反应性Human;Mouse;Rat
特异性Phospho-ERα (S104) Polyclonal Antibody detects endogenous levels of ERα protein only when phosphorylated at S104.
免疫原描述The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha around the phosphorylation site of Ser104. AA range:71-120
基因/蛋白名称Estrogen Receptor-α
标记Unconjugated
别名ESR1; ESR; NR3A1; Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1
数据库入口号Swiss Prot:P03372
GeneID:2099
Uniprot
P03372
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
estrogen receptor 1(ESR1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],
如果您使用该产品13884发表了文章，请通知我们，让我们可以引用您的文献。
et al,Hybrid-Ligand Metal–Organic Frameworks Enabling Radio–Radiodynamic–Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors
, (2025),
PMID:
40802503
Yes
