产品详情
产品名称c-Src (phospho-Tyr216) Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB,IHC-p,IF(paraffin section),ELISA
种属反应性Human;Mouse;Rat
特异性Phospho-c-Src (Y216) Polyclonal Antibody detects endogenous levels of c-Src protein only when phosphorylated at Y216.
免疫原描述The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr216. AA range:181-230
标记Unconjugated
别名SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
数据库入口号Swiss Prot:P12931
GeneID:6714
Uniprot
P12931
实际分子量50
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
Western Blot: 1/500 - 1/2000.
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/10000. Not yet tested in other applications.
SRC proto-oncogene, non-receptor tyrosine kinase(SRC) Homo sapiens This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
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et al,AURKA modulates tight junction functionality to influence the proliferation and metastasis of lung adenocarcinoma
, (2025),
PMID:
41201786
Yes
