产品详情
产品名称CPI-17 (phospho-Thr38) Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB;IHC;IF;ELISA
种属反应性Human;Mouse;Rat
特异性Phospho-CPI-17 (T38) Polyclonal Antibody detects endogenous levels of CPI-17 protein only when phosphorylated at T38.
免疫原描述The antiserum was produced against synthesized peptide derived from human CPI17 alpha around the phosphorylation site of Thr38. AA range:5-54
基因/蛋白名称PPP1R14A
标记Unconjugated
别名PPP1R14A; CPI17; PPP1INL; Protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17
数据库入口号Swiss Prot:Q96A00
GeneID:94274
Uniprot
Q96A00
实际分子量22
浓度1 mg/ml
配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
保存-20˚C/1
应用详情
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
protein phosphatase 1 regulatory inhibitor subunit 14A(PPP1R14A) Homo sapiens The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011],
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et al,TRPV4 maintains the contractile phenotype of VSMCs by regulating CPI-17
, (2025),
PMID:
40619010
Yes
