产品详情
产品名称CDK2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total CDK2 protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa.158~162 (T-Y-T-H-E) derived from Human CDK2.
基因/蛋白名称CDK2
标记Unconjugated
别名kinase Cdk2; p33 protein kinase;
数据库入口号Swiss-Prot: P24941
NCBI Protein: NP_001789.2
Uniprot
P24941
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 34kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from 293, MCF, 3T3 cells using CDK2(Ab-160) Antibody #21111.
Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
Ukomadu C, et al.(2003) J Biol Chem; 278(7): 4840-6
Morris MC, et al.(2002)J Biol Chem; 277(26): 23847-53
Brown NR, et al.(1999)J Biol Chem; 274(13): 8746-56
Liu Y, et al.(2004) J Biol Chem; 279(6): 4507-14
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et al,FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells. In J Biol Chem on 2011 Mar 25 by Song Chen, Hedeel Guy Evans, et al..PMID: 21148485
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et al,Pro-Apoptotic Effects of JDA-202, a Novel Natural Diterpenoid, on Esophageal Cancer Through Targeting Peroxiredoxin I.In Antioxid Redox Signal on 2017 Jul 10 by Xiao-Jing Shi , Lina Ding,et al..PMID: 27650197
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