产品详情
产品名称eNOS Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
应用IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total eNOS protein.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around aa.493~497 (K-K-T-F-K) derived from Human eNOS.
基因/蛋白名称eNOS
标记Unconjugated
别名Constitutive NOS; EC-NOS; ECNOS; NOS3; NOSIII
数据库入口号Swiss-Prot: P29474
NCBI Protein: NP_000594.2
Uniprot
P29474
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 140kd
Immunofluorescence: 1:100~1:200
Immunofluorescence staining of methanol-fixed Hela cells using eNOS(Ab-495) Antibody #21235.
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Moreno H Jr.(2008)Breast Cancer Res Treat. 109(1):181-2.
Lorenz M,et al.(2007)FASEB J. May;21(7):1556-64.
Lin HI,et al.(2006)Transplant Proc. Sep;38(7):2203-6.
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PMID:
40543847
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