产品详情
产品名称CD314 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Purified by antigen-affinity chromatography.
应用WB IHC
种属反应性Human
免疫原类型Peptide
免疫原描述Synthetic peptide contain a sequence corresponding to a region within amino acids 86 and 147 of CD314
基因/蛋白名称CD314
标记Unconjugated
数据库入口号NCBI Gene ID: 22914
NCBI mRNA#: NM_007360
NCBI Protein#: NP_031386
浓度0.8mg/ml
配方Supplied in 1XPBS, 40% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
保存Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
应用详情
Predicted MW: 25kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:50-1:500
Sample (30 ug of whole cell lysate)
A: A549
12% SDS PAGE
CD314 antibody diluted at 1: 1000
Immunohistochemical analysis of paraffin-embedded Gastric ca, using NKG2D antibody at 1: 500 dilution.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq]
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et al,Molecular Imaging of B7–H3–Targeting Bispecific T Cell–Engaging Antibody MGD009 in Glioblastoma Models
, (2025),
PMID:
40183579