产品详情
产品名称TLR2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化TLR2 Antibody is affinity chromatography purified via peptide column.
应用ELISA WB IHC
种属反应性Human;Mouse
免疫原类型Peptide
免疫原描述Raised against a peptide corresponding to 14 amino acids near the amino terminus of human TLR2.
基因/蛋白名称TLR2
标记Unconjugated
别名TIRAP, MAL, TIR domain containing adaptor protein
数据库入口号O60603
Uniprot
O60603
浓度1mg/ml
配方Supplied in PBS containing 0.02% sodium azide.
保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
应用详情
Western blot analysis of TLR2 in A20 cell lysates with TLR2 antibody at 1 ug/mL in the presence (A) and absence (B) of its blocking peptide.
Immunohistochemical staining of human spleen cells using TLR2 antibody at 2 ug/mL.
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κB. TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer can recognize a variety of bacterial and mycoplasma lipoproteins respectively.
如果您使用该产品24192发表了文章，请通知我们，让我们可以引用您的文献。
et al,Single-cell analysis reveals the immune heterogeneity and interactions in lungs undergoing hepatic ischemia-reperfusionInInt ImmunopharmacolOn2023 NovbyChen Zhang1,Mingwei Sheng2, et al..PMID:37844464
, (2023),
PMID:
37844464
有货
