产品详情
产品名称SRPX2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Affinity chromatography purified via peptide column
应用ELISA WB IHC
种属反应性Human;Mouse;Rat
免疫原类型Peptide
免疫原描述Raised against a 16 amino acid peptide from near the amino terminus of human SRPX2.
基因/蛋白名称SRPX2
标记Unconjugated
别名Sushi-repeat-containing protein X-linked 2, BPP, CBPS, PMGX, SRPUL
数据库入口号NP_055282
Uniprot
NP_055282
浓度1mg/ml
配方Supplied in PBS containing 0.02% sodium azide.
保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
应用详情
Western blot analysis of SRPX2 in human lung tissue lysate with SRPX2 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of SRPX2 in rat lung tissue with SRPX2 antibody at 5 ug/mL.
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
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et al,Atad3 is Essential for Mitochondrial Permeability Transition Pore Opening and Cardiac Ischemia Reperfusion Injury
, (2025),
PMID:
40667381
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