产品详情
产品名称ATG9B Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Affinity chromatography purified via peptide column
应用ELISA WB ICC
种属反应性Human;Mouse;Rat
免疫原类型Peptide
免疫原描述Raised against a 17 amino acid peptide near the carboxy terminus of human ATG9B.
基因/蛋白名称ATG9B
标记Unconjugated
别名Autophagy-related protein 9B, APG9L2, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, NOS3AS
数据库入口号NP_775952
Uniprot
NP_775952
浓度1mg/ml
配方Supplied in PBS containing 0.02% sodium azide.
保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
应用详情
Western blot analysis of ATG9B in HeLa cell lysate with ATG9B antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry of ATG9B in HeLa cells with ATG9B antibody at 10 ug/mL.
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it’s highly expressed in placenta and pituitary gland.
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et al,Depletion of CPNE7 sensitizes colorectal cancer to 5-fluorouracil by downregulating ATG9B expression. In J Cell Mol Med
on 2024 Apr by Weile Xu, Yujie Tang,et al..PMID:38526029
, (2024),
PMID:
38526029
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