产品详情
产品名称SHISA9 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Affinity chromatography purified via peptide column
应用ELISA WB IHC
种属反应性Human;Mouse;Rat
免疫原类型Peptide
免疫原描述Raised against a 22 amino acid peptide near the center of human SHISA9.
基因/蛋白名称SHISA9
标记Unconjugated
别名Cystine-knot AMPAR modulating protein 44a, CKAMP44a, CKAMP44, FLJ10015
数据库入口号B4DS77
Uniprot
B4DS77
浓度1mg/ml
配方Supplied in PBS containing 0.02% sodium azide.
保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
应用详情
Western blot analysis of SHISA9 in rat brain tissue lysate with SHISA9 antibody at 1 ug/mL.
Immunohistochemistry of SHISA9 in human brain tissue with SHISA9 antibody at 2.5 ug/mL.
Shisa proteins are a recently-identified family of modulators of both FGF and Wnt signaling that block both maturation and transport to the cell surface of their respective receptors. SHISA9, also known as CKAMP44a, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. It is thought to modulate short-term plasticity at specific excitatory synapses.
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et al,LncRNA ZFAS1 Combined with SRSF1 Regulate CNPY2 Expression and Leads to Microglia Endoplasmic Reticulum Stress–Induced Spinal Cord Injury
, (2025),
PMID:
40465066
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