产品详情
产品名称IL36G Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Mouse
免疫原描述Recombinant fusion protein of mouse IL36G (NP_705731.2).
标记Unconjugated
别名IL36G; IL-1F9; IL-1H1; IL-1RP2; IL1E; IL1F9; IL1H1; IL1RP2; interleukin-36 gamma
数据库入口号Swiss-Prot#:_
NCBI Gene ID:215257
Uniprot
Q9NZH8
计算分子量18kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of mouse liver, using IL36G antibody.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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et al,Metatranscriptome Reveals Specific Immune and Microbial Signatures of Respiratory Syncytial Virus Infection in ChildrenIn Microbiol Spectr On2023 Mar 2byQianyu Feng , Ziheng Feng et al..PMID:36861979
, (2023),
PMID:
36861979