产品详情
产品名称IKB alpha Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB;IP;ELISA
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human IKB alpha (NP_065390.1).
标记Unconjugated
别名NFKBIA; IKBA; MAD-3; NFKBI; NFKB inhibitor alpha
数据库入口号Swiss-Prot#:P25963
NCBI Gene ID:4792
Uniprot
P25963
计算分子量35kDa
实际分子量39kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500-1:2000; IP 1:20 - 1:50; ELISA 1:5000-1:20000
Western blot analysis of extracts from various cells using IKB alpha antibody.
Western blot analysis of extracts from normal (control) and IKB alpha knockout (KO) 293T cells using IKB alpha antibody.
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
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et al,5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis. In J Atheroscler Thromb on 2021 Feb 2 by Yingying Ma, Xiurui Liang,et al..PMID: 33536397
, (2021),
PMID:
33536397
et al,5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis In J Atheroscler Thromb on 2022 Mar 1 by Yingying Ma, Xiurui Liang,et al..PMID: 33536397
, (2022),
PMID:
33536397
et al,The Effect of Clostridium butyricum-Derived Lipoteichoic Acid on Lipopolysaccharide-Stimulated Porcine Intestinal Epithelial Cells.
, (2025),
PMID:
39749788
货期一周
