产品详情
产品名称CBX2 Antibody
来源种属Rabbit
克隆性Polyclonal
应用ELISA WB
种属反应性Human;Mouse
特异性The antibody detects endogenous level of total CBX2 protein.
免疫原类型Recombinant protein
免疫原描述Full length fusion protein
基因/蛋白名称CBX2
标记Unconjugated
别名chromobox homolog 2, M33, CDCA6, SRXY5
数据库入口号Genbank No.: BC004252
Uniprot
BC004252
浓度0.72mg/ml
配方Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
保存Store at -20˚C/1 year
应用详情
Predicted MW: 23kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Gel: 12+10%SDS-PAGE
Lane1: Human ovarian cancer tissue lysate
Lane2: Mouse heart tissue lysate
Lysates: 30ug per lane
Primary antibody: 1/350 dilution
Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Exposure time: 20 seconds
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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et al,The predictive significance of chromobox family members in prostate cancer in humans. In Cell Oncol (Dordr) on 2024 Aug by
Xiaoting Xu, Cong Lai,et al..PMID:38427207
, (2024),
PMID:
38427207