产品详情
产品名称IGF1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total IGF1 protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human IGF1.
基因/蛋白名称IGF1
标记Unconjugated
别名IGF1; IGF1A; IGFI;
数据库入口号Swiss-Prot:P05019
NCBI Gene ID:3479
Uniprot
P05019
实际分子量17KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded rat brain using IGF1 antibody at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using IGF1 antibody at 1:1000 dilution.
IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF1A.
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et al,Metal-HisTag coordination for remote loading of very small quantities of biomacromolecules into PLGA microspheres. In Bioeng Transl Med on 2022 Feb 17 by
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PMID:
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