产品详情
产品名称DCN Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB IHC IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total DCN protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human DCN.
基因/蛋白名称DCN
标记Unconjugated
别名CSCD; DSPG2; PG40; PGII; PGS2
数据库入口号Swiss-Prot:P07585
NCBI Gene ID:1634
Uniprot
P07585
实际分子量30KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100
Immunofluorescence: 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using DCN antibody.
Immunofluorescence analysis of MCF7 cell using DCN antibody. Blue: DAPI for nuclear staining.
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
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PMID:
39334513
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