产品详情
产品名称CADM2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total CADM2 protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from internal of human CADM2.
基因/蛋白名称CADM2
标记Unconjugated
别名Cell adhesion molecule 2 [Precursor]; Immunoglobulin superfamily member 4D; Nectin-like protein 3; CADM2; IGSF4D
数据库入口号Swiss-Prot: Q8N3J6
NCBI Gene ID: 253559
Uniprot
Q8N3J6
实际分子量47kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from HepG2 cells, using CADM2 antibody #34182.
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
Gingrich J.R., D'Angelo A., Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
The German cDNA consortium, Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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et al,Cell adhesion molecule 2 inhibits colorectal cancer progression through attenuating epithelial-mesenchymal transition
, (2024),
PMID:
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