产品详情
产品名称IL18BP Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total IL18BP protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from internal of human IL18BP.
基因/蛋白名称IL18BP
标记Unconjugated
别名Interleukin-18-binding protein; IL-18BP; Tadekinig-alfa; IL18BP;
数据库入口号Swiss-Prot: O95998
NCBI Gene ID: 10068
Uniprot
O95998
实际分子量44kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from HepG2 and HeLa cells, using IL18BP antibody #35224.
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Moss B., Virology 257:297-302(1999).
Sugano S., Nat. Genet. 36:40-45(2004).
Sakaki Y., Nature 440:497-500(2006).
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PMID:
40633861