产品详情
产品名称P2RY1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total P2RY1 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human purinergic receptor P2Y, G-protein coupled, 1
基因/蛋白名称P2RY1
标记Unconjugated
别名P2Y1
数据库入口号Swiss-Prot#: P47900
NCBI Gene ID: 5028
Gene Accssion: NP_002554/P47900
Uniprot
P47900
实际分子量42kd
浓度2.8mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
Gel: 10%SDS-PAGE
Lysates (from left to right): A549 cell and mouse liver tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 30 seconds
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #37007 at dilution 1/40.
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
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et al,Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1
, (2025),
PMID:
39251858
et al,Structure-Based Discovery of Quinazolin-2-amine Derivatives as Potent ROR1 Pseudokinase Inhibitors with In Vitro and In Vivo Efficacy against Triple-Negative …
, (2025),
PMID:
40736991
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