产品详情
产品名称ANKRA2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ANKRA2 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human ankyrin repeat, family A (RFXANK-like), 2
基因/蛋白名称ANKRA2
标记Unconjugated
别名ANKRA
数据库入口号Swiss-Prot#: Q9H9E1
NCBI Gene ID: 57763
Gene Accssion: NP_075526
Uniprot
Q9H9E1
浓度1.9mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37102 at dilution 1/50.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37102 at dilution 1/50.
This protein may facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery. ANKRA2 is a megalin- and BKCa potassium channel-interacting factor. It is a protein known to interact with HDAC4 and HDAC5.ANKRA2 is important for transcriptional repression by AhRR.
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et al,Hybrid-Ligand Metal–Organic Frameworks Enabling Radio–Radiodynamic–Chemodynamic Therapy Primes Checkpoint Blockade Immunotherapy in Hypoxic Tumors
, (2025),
PMID:
40802503