产品详情
产品名称MUC2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total MUC2 protein.
免疫原类型Peptide
免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human mucin 2, oligomeric mucus/gel-forming
基因/蛋白名称MUC2
标记Unconjugated
别名MLP; SMUC; MUC-2
数据库入口号Swiss-Prot#: Q02817
NCBI Gene ID: 4583
Gene Accssion: NP_002448
Uniprot
Q02817
浓度2mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #37169 at dilution 1/60.
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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et al,Nucleus-translocated glucokinase functions as a protein kinase to phosphorylate TAZ and promote tumour growth
, (2025),
PMID:
40759645
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