产品详情
产品名称BACH1 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total BACH1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human BACH1.
基因/蛋白名称BACH1
标记Unconjugated
别名BACH-1;
数据库入口号Swiss-Prot#: O14867
NCBI Gene ID: 571
Uniprot
O14867
实际分子量82kd
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunohistochemistry of paraffin-embedded rat ovary using BACH1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast cancer using BACH1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse liver using BACH1 antibody at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using BACH1 antibody at 1:3000 dilution.
Immunofluorescence analysis of HeLa cells using BACH1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.
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et al,Betaine-homocysteine methyltransferase protects against acetaminophen-induced acute liver failure via BACH1-SCD1-oleic acid axis
, (2025),
PMID:
40764413
Yes
