产品详情
产品名称VPS35 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total VPS35 protein.
免疫原类型protein
免疫原描述Fusion protein of human VPS35
基因/蛋白名称VPS35
标记Unconjugated
别名MEM3; PARK17
数据库入口号Swiss-Prot#: Q96QK1
Gene ID: 55737
Uniprot
Q96QK1
计算分子量92kd
浓度6.4mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:45-1:300
Gel: 6%SDS-PAGE
Lysate: 40 μg
Lane: Human fetal brain tissue
Primary antibody: 1/250 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #42841 at dilution 1/30.
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #42841 at dilution 1/30.
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.?
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et al,analysis: an analysis based on the European spontaneous adverse event reporting system
, (2025),
PMID:
39877384
Yes
