产品详情
产品名称GNLY Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total GNLY protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human GNLY
基因/蛋白名称GNLY
标记Unconjugated
别名LAG2; NKG5; LAG-2; D2S69E; TLA519
数据库入口号Swiss-Prot#: P22749
NCBI Gene ID: 10578
Uniprot
P22749
浓度0.5mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using GNLY Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
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et al,CD155 Cooperates with PD-1/PD-L1 to Promote Proliferation of Esophageal Squamous Cancer Cells via PI3K/Akt and MAPK Signaling Pathways. In Cancers (Basel) on 2022 Nov 15 by Xiyang Tan, Jie Yang, et al..PMID:36428703
, (2022),
PMID:
36428703
Yes
