产品详情
产品名称UTF1 Antibody
克隆号E0-F4
来源种属Mouse
克隆性Monoclonal
纯化ProA affinity purified
应用WB, ICC
种属反应性Human;Mouse;Rat
免疫原描述peptide
标记Unconjugated
别名hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody
数据库入口号Swiss-Prot#:Q5T230
Uniprot
Q5T230
计算分子量36-50 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:500-1:1000
ICC: 1:500-1:1,000
Western blot analysis on D3 cell lysates using anti- UTF1 mouse mAb.
ICC staining UTF1 in D3 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells.
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et al,One-Pot Preparation of an Antioxidant, Anti-Inflammatory, and Analgesic Hydrogel for Oral Mucosal Lesions
, (2025),
PMID:
40522041
Yes
