产品详情
产品名称PI3 Kinase p85 alpha Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Immunogen affinity purified.
应用WB, ICC, IHC, FC
种属反应性Human;Mouse;Rat
免疫原描述Synthetic peptide within human PI3-kinase p85 subunit alpha.
标记Unconjugated
别名GRB1 antibody p85 alpha antibody p85 antibody P85A_HUMAN antibody Phosphatidylinositol 3 kinase associated p 85 alpha antibody Phosphatidylinositol 3 kinase regulatory 1 antibody Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha) antibody Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody Phosphatidylinositol 3-kinase regulatory subunit alpha antibody Phosphoinositide 3 kinase, regulatory subunit 1 (alpha) antibody PI3 kinase p85 subunit alpha antibody PI3-kinase regulatory subunit alpha antibody PI3-kinase subunit p85-alpha antibody PI3K antibody PI3K regulatory subunit alpha antibody Pik3r1 antibody PtdIns 3 kinase p85 alpha antibody PtdIns-3-kinase regulatory subunit alpha antibody PtdIns-3-kinase regulatory subunit p86-alpha antibody
数据库入口号Swiss-Prot#:P27986
Uniprot
P27986
计算分子量85kDa
实际分子量85kDa
配方1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB 1:500-2000; IHC 1:50-200; ICC 1:50-200; FC 1:50-100
Western blot analysis of extracts from various cell lines using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Immunohistochemical analysis of paraffin-embedded Mouse testis using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Immunohistochemical analysis of paraffin-embedded Human placenta using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Immunohistochemical analysis of paraffin-embedded Mouse kidney tissue using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Immunofluorescence analysis of Human placenta tissue using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Immunofluorescence analysis of MCF7 cells using PI3 Kinase p85 alpha Rabbit Polyclonal Antibody.
Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. Mutations in PIK3R1 are implicated in cases of breast cancer.Mutations in PIK3R1 are associated to SHORT syndrome.
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