产品详情
产品名称LDHA Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Peptide affinity purified
应用WB, IHC, FC
种属反应性Human;Mouse;Rat
免疫原描述peptide
标记Unconjugated
别名Cell proliferation-inducing gene 19 protein antibody;GSD11 antibody; L lactate dehydrogenase A chain antibody; L-lactate dehydrogenase A chain antibody; l7R2 antibody; Lactate dehydrogenase 1, A chain antibody; Lactate dehydrogenase A antibody;Lactate dehydrogenase A4 antibody； Lactate dehydrogenase M antibody；LDH A antibody； LDH M antibody；LDH muscle subunit antibody； LDH muscle subunit; M LDH antibody； LDH-A antibody；LDH-M antibody； LDH1 antibody； ldha antibody； LDHA_HUMAN antibody； LDHM antibody； OTTMUSP00000017774 antibody； PIG19 antibody； Proliferation-inducing gene 19 antibody；Renal carcinoma antigen NY-REN-59 antibody
数据库入口号Swiss-Prot#:P00338
Uniprot
P00338
计算分子量37 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:500
IHC: 1:200
FC: 1:100-1:200
Western blot analysis of LDHA on different cell lysates using anti-LDHA antibody at 1/500 dilution. Positive control: Lane 1: A549 Lane 2: Hela Lane 3: A431 Lane 4: 293 Lane 5: Jurkat Lane 6: MCF-7 Lane 7: Human liver Lane 8: Human kidney Lane 9: Human brain Lane 10: Human thymus
Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.
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et al,FGL1-mediated lymph node metastasis in stage T1 non-small cell lung cancer: therapeutic targeting
, (2025),
PMID:
41024301
Yes
