产品详情
产品名称SDF1 Rabbit mAb
克隆号JJ09-20
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
纯化ProA affinity purified
应用WB, ICC/IF
种属反应性Human
免疫原描述recombinant protein
标记Unconjugated
别名12-O-tetradecanoylphorbol 13-acetate repressed protein 1 antibody AI174028 antibody C-X-C motif chemokine 12 antibody Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) antibody Chemokine (C-X-C motif) ligand 12 antibody Chemokine CXC motif ligand 12 antibody cxcl12 antibody hIRH antibody hSDF-1 antibody Intercrine reduced in hepatomas antibody IRH antibody OTTHUMP00000019491 antibody PBSF antibody Pre-B cell growth-stimulating factor antibody SCYB12 antibody SDF 1 antibody SDF-1 antibody SDF-1-alpha(3-67) antibody SDF-1a antibody SDF-1b antibody SDF1_HUMAN antibody SDF1A antibody SDF1B antibody Stromal cell-derived factor 1 antibody Stromal cell-derived factor 1 delta antibody Stromal cell-derived factor 1 gamma antibody Stromal cell-derived factor 1a antibody Stromal cell-derived factor-1 alpha antibody Thymic lymphoma cell-stimulating factor antibody Tlsf antibody TLSF-a antibody TLSF-b antibody Tlsfa antibody Tlsfb antibody TPAR1 antibody
数据库入口号Swiss-Prot#:P48061
Uniprot
P48061
计算分子量11 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000-1:2,000
ICC: 1:50-1:200
ICC staining SDF1 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining SDF1 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining SDF1 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1α and SDF1β) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.
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