产品详情
产品名称AKR1C2 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human AKR1C2 (NP_995317.1).
标记Unconjugated
别名AKR1C2;AKR1C-pseudo;BABP;DD;DD-2;DD/BABP;DD2;DDH2;HAKRD;HBAB;MCDR2;SRXY8;TDD
数据库入口号Uniprot:P52895
GeneID:1646
Uniprot
P52895
Gene ID
1646
计算分子量15kDa/36kDa
实际分子量37kDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using AKR1C2 antibody.
Immunohistochemistry of paraffin-embedded rat liver using AKR1C2 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human liver cancer using AKR1C2 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human Colon cancer using AKR1C2 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse liver using AKR1C2 Rabbit pAb.
Immunofluorescence analysis of L929 cells using AKR1C2 Polyclonal Antibody.
Immunofluorescence analysis of U-2 OS cells using AKR1C2 Polyclonal Antibody.
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
如果您使用该产品53172发表了文章，请通知我们，让我们可以引用您的文献。
et al,Corilagin alleviates radiation enteritis through caspase-1/gasdermin D-dependent pyroptosis by targeting aldo-keto reductase family 1 member C2 via glutathione …
, (2025),
PMID:
40674841
Yes
