产品详情
产品名称ULBP1 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse
免疫原描述Recombinant fusion protein of human ULBP1 (NP_079494.1).
标记Unconjugated
别名ULBP1;N2DL-1;NKG2DL1;RAET1I
数据库入口号Swiss Prot:Q9BZM6
GeneID:80329
Uniprot
Q9BZM6
计算分子量27kDa
实际分子量28kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:2000 - 1:5000
IHC 1:50 - 1:200
Western blot analysis of extracts of Raji cells, using ULBP1 at 1:1000 dilution.
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
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et al,p14ARF interacts with γ-H2AX and is involved in the DNA damage response
, (2025),
PMID:
40267841
Yes
