产品详情
产品名称SOX2 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human SOX2 (NP_003097.1).
标记Unconjugated
别名ANOP3;MCOPS3;SOX2;SRY-box 2
数据库入口号Swiss Prot:P48431
GeneID:6657
Uniprot
P48431
计算分子量34kDa
实际分子量38kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using SOX2 at 1:1000 dilution.
Immunofluorescence analysis of C6 cells using SOX2 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HeLa cells using SOX2 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Confocal immunofluorescence analysis of U-2 OS cells using SOX2 Polyclonal at dilution of 1:200. Blue: DAPI for nuclear staining.
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
如果您使用该产品53255发表了文章，请通知我们，让我们可以引用您的文献。
et al,Cyclin E1 is dispensable for skin homeostasis and hyperplasia but is essential for carcinogenesis.
, (2025),
PMID:
41260952
Yes
