产品详情
产品名称HDGF Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human
免疫原描述Recombinant fusion protein of human HDGF (NP_004485.1).
标记Unconjugated
别名HDGF;HMG1L2
数据库入口号Swiss Prot:P51858
GeneID:3068
Uniprot
P51858
计算分子量25kDa/26kDa/28kDa
实际分子量37kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunofluorescence analysis of HeLa cells using HDGF at dilution of 1:50. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using HDGF at 1:1000 dilution.
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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et al,A KAT7-lncPVT1 positive feedback loop promotes lung cancer carcinogenesis and therapy resistance via H3K14ac/HDGF/PI3K/AKT Axis
, (2025),
PMID:
41418975
Yes
