产品详情
产品名称FTO Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human FTO (NP_001073901.1).
标记Unconjugated
别名FTO;ALKBH9;BMIQ14;GDFD
数据库入口号Uniprot:Q9C0B1
GeneID:79068
Uniprot
Q9C0B1
Gene ID
79068
计算分子量6kDa/12kDa/14kDa/58kDa
实际分子量60KDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using FTO antibody.
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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et al,MiR-27a-3p protects against NaAsO2-induced neuronal apoptosis in HT22 cells
, (2025),
PMID:
40269215
Yes
