产品详情
产品名称INHBB Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse
免疫原描述Recombinant fusion protein of human INHBB (NP_002184.2).
标记Unconjugated
别名INHBB
数据库入口号Uniprot:P09529
GeneID:3625
Uniprot
P09529
Gene ID
3625
计算分子量45kDa
实际分子量45kDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using INHBB antibody.
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
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et al,Nucleus-translocated glucokinase functions as a protein kinase to phosphorylate TAZ and promote tumour growth
, (2025),
PMID:
40759645
Yes
