产品详情
产品名称Recombinant rat Basic leucine zipper transcriptional factor ATF-like 3
来源种属E.coli
基因/蛋白名称BATF3
别名Jun dimerization protein 1 ;JDP-1
数据库入口号Uniprot ID: P97876
Uniprot
P97876
计算分子量19.22kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属RAT
Target长度Full length, 1-133aa
Tag InfoHis-tag
Target序列MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune syst. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. Required for development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens .
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