产品详情
产品名称Recombinant bovine Inhibin alpha chain
来源种属E.coli
基因/蛋白名称INHA
数据库入口号Uniprot ID: P07994
Uniprot
P07994
计算分子量30.7kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属BOVIN
Target长度Full length of Inhibin alpha chain, 227-360aa
Tag InfoHis-SUMO-tag
Target序列SSTPPLPWPWSPAALRLLQRPPEEPAAHADCHRAALNISFQELGWDRWIVHPPSFIFYYCHGGCGLSPPQDLPLPVPGVPPTPVQPLSLVPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYEMVPNLLTQHCACI
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, bryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
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et al,Discovery of novel and potent InhA direct inhibitors by ensemble docking-based virtual screening and biological assaysInJ Comput Aided Mol DesOn2023 DecbyQianqian Zhang , Jianting Han et al..PMID:37642861
, (2023),
PMID:
37642861
15-30工作日
