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EDNRB antibody#38492

EDNRB antibody
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产品总价:
产品详情

产品名称EDNRB antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were purified by affinity purification using immunogen.

应用WB

种属反应性Human,Mouse

特异性The antibody detects endogenous level of total EDNRB protein.

免疫原类型Peptide

免疫原描述A synthetic peptide of human EDNRB .

基因/蛋白名称EDNRB

别名ETB;ET-B;ETBR;ETRB;HSCR;WS4A;ABCDS;ET-BR;HSCR2;

数据库入口号Swiss-Prot#: P24530
NCBI Gene ID: 1910

UniprotP24530

实际分子量50kd

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using EDNRB antibody at 1:1000 dilution.
背景
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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