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METTL13 Polyclonal Antibody#27722

METTL13 Polyclonal Antibody
METTL13 Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称METTL13 Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF

种属反应性Human

免疫原描述Recombinant fusion protein of human METTL13 (NP_057019.3).

别名METTL13;5630401D24Rik;CGI-01;KIAA0859;feat

数据库入口号Uniprot:Q8N6R0
GeneID:51603

UniprotQ8N6R0

Gene ID51603

计算分子量85kDa

实际分子量85kDa

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of MCF7 cells, using METTL13 antibody.
Immunofluorescence analysis of A549 cells using METTL13 antibody.
背景
Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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