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位置: 首页 > 抗体 > MCAM Rabbit Polyclonal Antibody

MCAM Rabbit Polyclonal Antibody#53745

MCAM Rabbit Polyclonal Antibody
MCAM Rabbit Polyclonal Antibody
MCAM Rabbit Polyclonal Antibody
MCAM Rabbit Polyclonal Antibody
MCAM Rabbit Polyclonal Antibody
MCAM Rabbit Polyclonal Antibody
MCAM Rabbit Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称MCAM Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC,IF

种属反应性Human,Mouse,Rat

免疫原描述Recombinant fusion protein of human CD146/CD146/MCAM (NP_006491.2).

别名MCAM;CD146;MUC18

数据库入口号Uniprot:P43121
GeneID:4162

UniprotP43121

Gene ID4162

计算分子量57kDa/71kDa

实际分子量120KDa

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using CD146/MCAM antibody.
Western blot analysis of extracts of various cell lines, using CD146/MCAM antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using CD146/MCAM Rabbit pAb.
Immunohistochemistry of paraffin-embedded human lung cancer using CD146/MCAM Rabbit pAb.
Immunohistochemistry of paraffin-embedded human lung using CD146/MCAM Rabbit pAb.
Immunofluorescence analysis of A375 cells using CD146/MCAM Rabbit pAb.
Immunofluorescence analysis of HeLa cells using CD146/MCAM Rabbit pAb.
背景
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

techcn@signalwayantibody.com