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位置: 首页 > 单克隆抗体 > CBL (Phospho-Tyr774) Rabbit mAb

CBL (Phospho-Tyr774) Rabbit mAb#14270

CBL (Phospho-Tyr774) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称CBL (Phospho-Tyr774) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC FC

种属反应性Human

特异性Phospho-CBL (Y774) Antibody detects endogenous levels of total Phospho-CBL (Y774)

免疫原描述A synthesized peptide derived from human Phospho-CBL (Y774)

别名Casitas B lineage lymphoma proto oncogene; CBL2; E3 ubiquitin protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; RING finger protein 55; RNF55; Signal transduction protein CBL;

数据库入口号Uniprot:P22681

UniprotP22681

计算分子量120kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200
FC:1:50
Western blot analysis of Phospho-CBL (Y774) expression in Jurkat cell treated with Pervanadate lysate.
产品描述
Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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