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位置: 首页 > 磷酸化抗体 > Estrogen Receptor- beta (Phospho-Ser105) Antibody

Estrogen Receptor- beta (Phospho-Ser105) Antibody#11998

Estrogen Receptor- beta (Phospho-Ser105) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Estrogen Receptor- beta (Phospho-Ser105) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of Estrogen Receptor- beta only when phosphorylated at serine 105.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of serine105(Q-R-S(p)-P-W) derived from Human Estrogen Receptor- beta.

基因/蛋白名称Estrogen Receptor- beta

修饰Phospho

别名ESR2; ESTRB; Estrogen receptor beta; NR3A2;

数据库入口号Swiss-Prot#: Q92731;
NCBI Gene#: 2100;
NCBI Protein#: NP_001035365.1

UniprotQ92731

实际分子量59kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HepG2 tissue using Estrogen Receptor- beta (Phospho-Ser105) antibody #11998.The lane on the right is treated with the antigen-specific peptide.
背景

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Hamilton-Burke W, et al. (2010)Am J Pathol 177, 1079-86. St-Laurent V, Sanchez M, Charbonneau C, Tremblay A (2005) J Steroid Biochem Mol Biol 94, 23-37. Tremblay A, Tremblay GB, Labrie F, Gigu¨¨re V (1999) Mol Cell 3, 513-9 .

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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