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位置: 首页 > 磷酸化抗体 > VEGFR1 (Phospho-Tyr1048) Antibody

VEGFR1 (Phospho-Tyr1048) Antibody#11759

VEGFR1 (Phospho-Tyr1048) Antibody
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产品总价:
产品详情

产品名称VEGFR1 (Phospho-Tyr1048) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu

特异性The antibody detects endogenous levels of VEGFR1 only when phosphorylated at tyrosine 1048.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 1048 (D-I-Y(p)-K-N) derived from Human VEGFR1.

基因/蛋白名称VEGFR1

修饰Phospho

别名VGFR1; FRT; FLT1; FLT;

数据库入口号Swiss-Prot#: P17948;
NCBI Gene#: 2321;
NCBI Protein#: NP_002010.2.

UniprotP17948

实际分子量150kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Immunohistochemistry: 1:50~1:100

Immunohistochemical analysis of paraffin-embedded human brain tissue using VEGFR1 (Phospho-Tyr1048) antibody #11759 (left)or the same antibody preincubated with blocking peptide (right).
背景

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Shibuya M., Oncogene 5:519-524(1990).
Kendall R.L., Proc. Natl. Acad. Sci. U.S.A. 90:10705-10709(1993).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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