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MCL1 Antibody#33430

MCL1 Antibody
MCL1 Antibody
MCL1 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称MCL1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of total MCL1 protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from human MCL1.

基因/蛋白名称MCL1

别名EAT/MCL-1 protein; Induced myeloid leukemia cell differentiation protein Mcl-1; Myeloid cell leukemia sequence 1.;

数据库入口号Swiss-Prot: Q07820
NCBI Gene ID: 4170

UniprotQ07820

实际分子量37kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MCL1 antibody #33430.
Western blot analysis of extracts from HuvEc cells, using MCL1 antibody #33430.
Western blot analysis of extracts from HuvEc cells (Lane 2), JK cells (Lane 3) and cos-7 cells (Lane 4), using MCL1 antiobdy #33430. The lane on the left is treated with synthesized peptide.
背景
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Alfredo De Biasio, J. Biol. Chem., Jun 2007; 10.1074.
Potchanapond Graidist, J. Biol. Chem., Sep 2004; 279: 40868 - 40875.
Kenichi Fujise, J. Biol. Chem., Dec 2000; 275: 39458.
Di Zhang, J. Biol. Chem., Sep 2002; 277: 37430 - 37438.

如果您使用该产品33430发表了文章,请通知我们,让我们可以引用您的文献。

et al,Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. In PLoS One on 2012 by Manujendra N Saha, Hua Jiang, et al..PMID: 22276160, , (2012),
PMID: 22276160
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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