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JHD3B Antibody#33623

JHD3B Antibody
是否有货: 有货
产品总价:
产品详情

产品名称JHD3B Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用IHC

种属反应性Hu

特异性The antibody detects endogenous levels of total JHD3B protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from C-terminal of human JHD3B.

基因/蛋白名称JHD3B

别名EC 1.14.11.-; JMJ2B; Jumonji domain containing protein 2B;

数据库入口号Swiss-Prot: O94953
NCBI Gene ID: 23030

UniprotO94953

实际分子量122kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情

Immunohistochemistry: 1:50~1:100
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JHD3B antibody #33623.
背景
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Nagase T., DNA Res. 5:355-364(1998).
Nakajima D., DNA Res. 9:99-106(2002).
Grimwood J., Nature 428:529-535(2004).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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