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位置: 首页 > 抗体 > ZC3H8 Antibody

ZC3H8 Antibody#35154

ZC3H8 Antibody
ZC3H8 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称ZC3H8 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB IHC

种属反应性Hu

特异性The antibody detects endogenous levels of total ZC3H8 protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from internal of human ZC3H8.

基因/蛋白名称ZC3H8

别名Zinc finger CCCH domain-containing protein 8; ZC3H8; ZC3HDC8;

数据库入口号Swiss-Prot: Q8N5P1
NCBI Gene ID: 84524

UniprotQ8N5P1

实际分子量40kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from HepG2 cells, using ZC3H8 antibody #35154.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ZC3H8 antibody #35154.
背景
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Hwang E.S., Immunology 106:464-469(2002).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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