产品详情
产品名称Stathmin1(Phospho-Ser25) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of Stathmin 1 only when phosphorylated at serine 25.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around phosphorylation site of serine 25 (I-L-S(p)-P-R) derived from Human Stathmin 1.
基因/蛋白名称Stathmin1
标记Unconjugated
别名STMN1; STN1; stathmin
数据库入口号Swiss-Prot: P16949
NCBI Protein: NP_001138926.1
Uniprot
P16949
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 19kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from Jurkat cells untreated or treated with PMA using Stathmin 1(Phospho-Ser25) Antibody #11224.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1(Phospho-Ser25) Antibody #11224(left) or the same antibody preincubated with blocking peptide(right).
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
Boehm M, et al. (2002) EMBO J 21(13): 3390-3401.
Vadlamudi RK, et al. (2005) Mol Cell Biol 25(9): 3726-3736.
Zilfou JT, et al. (2001) Mol Cell Biol 21(12): 3974-3985.
Biernat J, et al. (2002) Mol Biol Cell 13(11): 4013-4028.
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et al,One-Pot Preparation of an Antioxidant, Anti-Inflammatory, and Analgesic Hydrogel for Oral Mucosal Lesions
, (2025),
PMID:
40522041
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