产品详情
产品名称SCN8A Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human
免疫原描述Recombinant fusion protein of human SCN8A (NP_055006.1).
标记Unconjugated
别名SCN8A; BFIS5; CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4; sodium channel protein type 8 subunit alpha
数据库入口号Swiss-Prot#:Q9UQD0
NCBI Gene ID:6334
Uniprot
Q9UQD0
计算分子量165kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:200 - 1:1000
Western blot analysis of extracts of various cell lines, using SCN8A antibody.
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
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et al,Serine Supplementation Attenuates High-Selenium-Induced Insulin Resistance via Feedback Inhibition of PHGDH in Mice
, (2025),
PMID:
41264177
Yes
