产品详情
产品名称PPP1R14A Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human PPP1R14A (NP_150281.1).
标记Unconjugated
别名PPP1R14A; CPI-17; CPI17; PPP1INL; protein phosphatase 1 regulatory subunit 14A
数据库入口号Swiss-Prot#:Q96A00
NCBI Gene ID:94274
Uniprot
Q96A00
计算分子量17kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using PPP1R14A antibody.
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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et al,TRPV4 maintains the contractile phenotype of VSMCs by regulating CPI-17
, (2025),
PMID:
40619010
Yes
